LOCUS       ISCR1-qnrA1_unit                    4226 bp    DNA     linear       26-OCT-2020
DEFINITION  Proteus mirabilis.
ACCESSION
VERSION
KEYWORDS    .
SOURCE      Proteus mirabilis
  ORGANISM  Proteus mirabilis
            Unclassified.
REFERENCE   1  (bases 1 to 4226)
  AUTHORS   Zhou,D.
  TITLE     The complete sequence of ISCR1-qnrA1_unit
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4226)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-OCT-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: HGAP v. v3.0
            Sequencing Technology :: PacBio
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..4226
                     /organism="Proteus mirabilis"
                     /mol_type="genomic DNA"
     mobile_element  1..4226
                     /gene="ISCR1-qnrA1 unit"
                     /product="Putative resistance unit: ISCR1-qnrA1 unit"
     mobile_element  complement(1..2154)
                     /gene="ISCR1"
                     /product="Insertion sequence: ISCR1"
     CDS             381..1922
                     /gene="tnpA"
                     /codon_start=1
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHHIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     misc_recomb     2134..2154
                     /gene="oriIS"
                     /product="ISCR1 oriIS"
     CDS             2186..2842
                     /gene="qnrA1"
                     /codon_start=1
                     /product="Quinolone resistance protein"
                     /translation="MDIIDKVFQQEDFSRQDLSDSRFRRCRFYQCDFSHCQLQDASFE
                     DCSFIESGAVEGCHFSYADLRDASFKACRLSLANFSGANCFGIEFRECDLKGANFSRA
                     RFYNQVSHKMYFCSAYISGCNLAYTNLSGQCLEKCELFENNWSNANLSGASLMGSDLS
                     RGTFSRDCWQQVNLRGCDLTFADLDGLDPRRVNLEGVKICAWQQEQLLEPLGVIVLPD
                     "
     CDS             3028..3903
                     /gene="ampR"
                     /codon_start=1
                     /product="LysR-family regulator"
                     /translation="MVRRYLPLNPLRAFEAAARHLSFTRAAIELNVTHAAVSQQVRAL
                     EEQLGCVLFTRVSRGLVLTHEGEGLLPVLNEAFDRIADTLECFSHGQFRERVKVGAVG
                     TFAAGWLLPRLAGFYDSHPHIDLHISTHNNHVDPAAEGHDYTIRFGNGAWHESDAELI
                     FSAPHAPLCSPAIAEQLQQPDDVHRFTLLRSFRRDEWSRWLDCAGGTPPSPSQPVMVF
                     DTSLAMAEAAQLGAGVAIAPVCMFSRLLQSGALVQPFAAEITLGGYWLTRLQSRTETP
                     AMQQFARWLLNTAAA"
     CDS             complement(3927..4166)
                     /gene="hypA"
                     /codon_start=1
                     /product="Hydrogenase nickel incorporation protein HypA"
                     /translation="MSGWKSAHWRMLRRVHCISVLISPAVIPWRRAAHCILMLSRHRH
                     GAGIAAVRPKSCSTPDAVRTAAVNGCASVKVMICG"
BASE COUNT      980 a   1205 c   1109 g    932 t
ORIGIN
        1 aatatctcct tttgggttgt taataaaaca tccaataagt tgactgtgcg tgaaaaagaa
       61 agttttgtgt gatggcgttg aagatcgcac cgttaagctc ttatgtggga tggtgcagag
      121 ctcgacgact accgataaaa cgcaaccgcc gcaaacagac aagaaaaagc cccaactgat
      181 aacagttggg gcttcagtat tgtgattggt ggagcaatag caccctgaac ccaaaacctt
      241 ctcgctcaac cggtagtggc tgataacaac tcgtgagggc tattgcgggt taagcattta
      301 gcgatgtcta gggccagact ggacgtctga acgcaagccg ctgatactgt acataaccac
      361 agtatcagcg gaggataccc atgtcgctgg caaggaacgc cacggcgagt caatcgccca
      421 ctcaaacaaa cggttacgaa cgccaccaac ccgaccagac gctgctctac cagctggttg
      481 agcagcacta cccagccttc aaagcctcac tcgaagccca aggtcaacac ctgcctcgct
      541 acatccaaca agaattcaac gacctcctcc aatgtggccg tctggagtat ggtttcatgc
      601 gggttcgctg cgaggattgt catcacgagc gtctggtcgc cttcagctgt aaacgacgcg
      661 gcttttgccc tagctgcggt gcccgccgga tggccgagag tgcggcgctg ctgatagacg
      721 aagtcttccc caaggagccc attcgccagt gggtgctcag ctttcctttc cagctacgct
      781 ttttgctggc tcgccatccc cagctgatgg gccaggtctt gagtatcgtc tatcgtacac
      841 tctcaactca tctgatcaaa aaagccggtt acaccaaagc ctctgcacaa actggctcag
      901 tgactcttat ccaacgcttt ggctccgcgc taaatctcaa tgtccactac cacatgctgt
      961 ttctcgatgg tgtctatgcc gaagatgact atggcaagca acgcttccat cgtgtcaagg
     1021 cacccactta cgatgagctg aatacgctcg ctcacaccct cagccatcac atcgctcgct
     1081 gcatggaaaa gcgtgggatt ttggagcgtg atgccgagaa tacgtggttg acactggaag
     1141 agggcgaaga cgatacgctg actcaattac atggtgcttc ggttacgtat cgcattgccg
     1201 tcggccccca gcaagggcgc aaagtcttca ccctgcaaac cttgccaggg cgtgaggata
     1261 aagccgactc aagcagtcga gtagccaacc atgctggttt ctcgctacac gccggtgtga
     1321 tggccgaagc gcatcagcgg gataagcttg agcgcttgtg tcgctacatt agtcggccag
     1381 cggtttcaga aaaacgtctg gcattaaccg ccaatgggca ggtgcgttac gagctcaaaa
     1441 ctccgtaccg caatggcacc acccatgtga tcttcgagcc gctggacttc atcgccaaac
     1501 tcgctgcgtt ggtacctaag ccgcgagtca acctcacacg cttccacggc gtctttgcac
     1561 cgaacagcaa acaccgagtt caagtaacac ccgccaagcg gggcaagaag cccgacaaat
     1621 cggaaggtct cgatactaac tggcgtgaca agagtcctgc agagcgccac cgcgccatga
     1681 cctggatgca acgcctcaag cgagtcttca atattgatat tgaagtctgc gaacactgcg
     1741 gcggtcacgt caaagtgatt gccagcatcg aagatccgaa ggtcattgag cagattctca
     1801 agcatctgaa acagaaaaca gccaaggcga atgccgccaa gcagcgtgag ctgccaccag
     1861 aacgagcgcc gccactgact cccagcctgt tcgatccatc acagagtcgt ctctttgact
     1921 gacgacccca aatccaacac tgctcaacac tgccaacttt taaacggggc ggtggggcag
     1981 tttgtatctc tcgagctatc aggctagaga ttttaccgcc aaatcgaacc ttattagagc
     2041 ggtttaggct ggaccggcag ttaaaattgg ggcttgagcg gtaaacgagt gagggaattt
     2101 caggtaagat acttcggatg aggagcaaaa aggtggttta tacttcctat acccgttagc
     2161 accctccctg attaaaggaa gccgtatgga tattattgat aaagtttttc agcaagagga
     2221 tttctcacgc caggatttga gtgacagccg ttttcgccgc tgccgctttt atcagtgtga
     2281 cttcagccac tgtcagctgc aggatgccag tttcgaggat tgcagtttca ttgaaagcgg
     2341 cgccgttgaa gggtgtcact tcagctatgc cgatctgcgc gatgccagtt tcaaggcctg
     2401 ccgtctgtct ttggccaact tcagcggtgc caactgcttt ggcatagagt tcagggagtg
     2461 cgatctcaag ggcgccaact tttcccgggc ccgcttctac aatcaagtca gccataagat
     2521 gtacttctgc tcggcttata tctcaggttg caacctggcc tataccaact tgagtggcca
     2581 atgcctggaa aaatgcgagc tgtttgaaaa caactggagc aatgccaatc tcagcggcgc
     2641 ttccttgatg ggctcagatc tcagccgcgg caccttctcc cgcgactgtt ggcaacaggt
     2701 caatctgcgg ggctgtgacc tgacctttgc cgatctggat gggctcgacc ccagacgggt
     2761 caacctcgaa ggagtcaaga tctgtgcctg gcaacaggag caactgctgg aacccttggg
     2821 agtaatagtg ctgccggatt agctcgaatg caaacacaag aggcaaatat cacttgagtt
     2881 ccgcgctaca acaaggcaga ttctgctata gcagagtatt accgccggaa tgccgtttct
     2941 ctgctgccgc agccgacgtt ataccttccc ttcaaaggag gcattatgaa gactcaactg
     3001 ccctaaagaa aaacttacag gtggattatg gtcagacgtt atctccccct taacccgctg
     3061 cgcgcctttg aggccgccgc ccgtcatctc agttttaccc gcgcggcgat tgagctgaat
     3121 gtcacccatg ccgccgtcag ccagcaggtc agggcgctgg aagaacaact cggctgtgtg
     3181 ctgtttaccc gcgtctcgcg cgggctggtg ctgacccatg aaggtgaggg attactgccg
     3241 gtgctcaatg aggcgtttga ccggattgcg gatactctgg agtgtttttc tcacgggcag
     3301 ttccgtgagc gggtgaaagt cggtgcggtg ggaacatttg ccgcaggctg gctgctgccg
     3361 cgtctggccg gattctatga cagccatccg catattgatc tgcatatctc cacccataac
     3421 aatcatgtgg acccggcggc ggaagggcat gattatacga tccgtttcgg taacggcgcg
     3481 tggcatgagt cagatgcgga actgattttc agtgcaccac acgctccgct gtgctcaccg
     3541 gccattgcag aacagttaca gcagccggat gatgttcacc gctttaccct gctgcgctca
     3601 ttccgccggg atgaatggag ccgctggctg gattgtgcgg gcggcacacc gccttccccg
     3661 tcacagccgg taatggtgtt cgatacctca ctggccatgg ccgaggcggc acaactgggt
     3721 gccggggtag cgatcgcacc ggtatgtatg ttcagccgcc tgttacagtc aggcgcactg
     3781 gtacagccgt ttgccgcaga aatcaccctc ggcggctact ggctgacgcg gttacagtcc
     3841 cgtacggaaa ccccggccat gcagcaattc gcccgctggc tgctgaatac ggcggcggcg
     3901 taaaactcac tcaccttcca ggctttttac ccgcaaatca tcaccttcac tgatgcgcag
     3961 ccgttcactg ccgcagtgcg gacagcatcc ggcgtgctgc atgatttcgg cctcacggct
     4021 gcaatcccag caccatgcct gtgccgggat aacatcaata tgcagtgtgc agccctgcgc
     4081 cacggtatca cggcaggcga tatcaaaaca gaaatgcagt gcactctcct caacatccgc
     4141 cagtgcgccg acttccagcc agacatccgt tacccgcgca atgccgtgct gttcagcctg
     4201 ttcgcggata atgtccgccg caccga
//
